HCG 5000 (Human Chorionic Gonadotropin), a polypeptide hormone produced by the human placenta, is composed of an alpha and a beta sub-unit.
HCG 5000 iu for injection, is a highly purified pyrogen-free preparation obtained from the urine of pregnant females. It is standardized by a biological assay procedure. It is available for intramuscular injection.
The action of is virtually identical to that of pituitary LH, although HCG 5000 iu appears to have a small degree of FSH activity as well. HCG 5000 iu stimulates production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testis to produce androgens and the corpus luteum of the ovary to produce progesterone. Androgen stimulation in the male leads to the development of secondary sex characteristics and may stimulate testicular descent when no anatomical impediment to descent is present. This descent is usually reversible when HCG 5000 iu is discontinued.
5000 iu HCG Men
The obvious use of course being to stimulate the production of endogenous testosterone. The activity of HCG 5000 iu in the male body is due to its ability to mimic LH (luteinizing hormone), a pituitary hormone that stimulates the Leydig’s cells in the testes to manufacture testosterone. Restoring endogenous testosterone production is a special concern at the end of each steroid cycle, a time when a subnormal androgen level (due to steroid induced suppression) could be very costly. The main concern is the action of cortisol, which in many ways is balanced out by the effect of androgens. Cortisol sends the opposite message to the muscles than testosterone, or to breakdown protein in the cell.
Left unchecked (by an extremely low testosterone level) in the body, cortisol can quickly strip much of your new muscle mass away. The main focus with HCG 5000 iu is to restore the normal ability of the testes to respond to endogenous luteinizing hormone. After a long period of inactivity, this ability may have been seriously reduced. In such a state testosterone levels may not reach a normal point, even though the release of endogenous LH has been resumed. Many who have suffered severe testicular shrinkage may be able to relate, as it is often some time before normal testicle size and feelings of virility are restored if ancillary drugs had not been used. The excessive stimulation brought forth by administration of HCG 5000 iu can likewise cause the testicles to rapidly return to their normal size and level of activity. We are not simply looking for it to fix the problem however, as the resulting high testosterone level can itself trigger negative feedback inhibition at the hypothalamus. Estrogen production is also heightened with the use of HCG 5000 iu, due to its ability to increase aromatase activity in the Leydig’s cells.
HCG Dosage 5000 iu
In very long or heavy short cycles, Hpta levels on body reduce dramatically. There are many ways to recover Hpta levels but none of them are quick and side affectless like HCG 5000 iu. Many athletes today prefer to use HCG 5000 iu in the last 3-4 weeks of their long cycles and following it 3-4 weeks after cycle’s end.
There are two common dosages of HCG 5000 iu as 500 mcg and 1000 mcg. But for many people, so high dose can cause too much aromatization and because of dangerous aromatization side effects, they must be used dose under 500 mcg. It will affect in longer period but will avoid also dangerous side effects. Many athletes inject 500iu in last 4 weeks of a cycle and then increase it to 1000iu once a week.
Active life of HCG 5000 iu is 5 days. Also it must be used at least 5 days after last injection because of long active life. Traces of HCG 5000 iu can be found till 3 months. Professional bodybuilders are also adding substances like bacteriostatic water to injection for gaining maximum benefit from HCG 5000 iu.