Proviron (Mesterolone) by Schering is an oral androgen (another name is 1-methyl dihydrotestosterone). Like dihydrotestosterone, mesterolone has great androgenic strength and just not sufficient enough anabolic strength. This is due to the fact that, like dihydrotestosterone, mesterolone is rapidly deactivated in muscle tissue to an inactive substance.
Proviron has an extremely high affinity for binding to plasma proteins such as SHBG (binding globulin in the sex hormones). This makes Mesterolone enhance the activity of other anabolic steroids.
Among athletes, Proviron is primarily used to increase androgen levels in the diet or in preparation for competition. It is well known for its anti-estrogenic effect, due to his own ability to antagonize the aromatase enzyme.
When taking Proviron, given are some of increases in muscle, even if minimal, more or less it’s about muscle hardness and density. It is known that androgen receptors are found in the muscle and in fat cells and therefore, the use of Mesterolone together with testosterone promotes muscle growth but also a loss of fat.
Proviron Schering Dosage
Standard Proviron doses to treat androgen or male fertility will normally fall in the 50-75mg per day range. Normally the total dosing is split into 2-3 25mg doses per day. In androgen deficiency plans, the total dosing almost always starts at 75mg per day and slowly reduces to 25-50mg per day depending on patient need.
In a performance capacity, Proviron by Schering doses normally range from 50-150mg per day. Most men, however, will find 100mg per day to be the minimum beneficial dose with both 100mg and 150mg being highly effective. Total use will normally last between 8-12 weeks. However, in an effort to breakthrough a sticking point in a cycle, say towards the end of a cycle a 6 week course of Proviron may do the trick.
When you’re planning your Proviron use, you will find it stacks well with all anabolic steroids. During the cutting phase it will be most beneficial in conjunction with steroids like Anavar, Masteron and Winstrol as well as Primobolan. It will greatly promote the androgenicity of these steroids in order to provide and promote the hard look desired. In a bulking phase, while it will stack well with all anabolic steroids it’s hard to say if you’ll need it or not. Some will simply keep it on hand and include it when it proves to be possibly necessarily beneficial.
Proviron Schering Side Effects
Because Proviron is a DHT-derivative, it carries with it no risks at any dosage for estrogenic side effects. In fact, as previously mentioned, Proviron acts as an anti-estrogen via its activity as an aromatase inhibitor in the body. This can result in the mitigation of estrogenic side effects from other compounds via the reduction of total circulating plasma levels of Estrogen. Research has demonstrated that because of this effect of Proviron, it has been utilized medically in the treatment of gynecomastia and breast cancers because of its strong androgenic nature combined with its anti-estrogenic capabilities.
Because Proviron is primarily an androgen, it does carry with it the risk of androgenic side effects, and they are more pronounced with higher dosages. Proviron’s androgenic side effects include: an increase in oily skin (as a result of increased sebum production/secretion), increased facial hair and bodily hair growth, as well as the increased risk of triggering MPB (Male Pattern Baldness) in those that are genetically sensitive or predisposed to it. Women are also prone to virilization through the use of Proviron, which is the development of male characteristics in females (i.e. deepening of the voice, facial hair growth, enlargement of the clitoris, etc.). It is also important to note that because Proviron is already a derivative of DHT, products such as Finasteride, Proscar, or Dutasteride will do absolutely nothing to reduce Proviron’s potential androgenic side effects.
Because Mesterolone is not C-17 alpha alkylated (it is instead methylated on its first carbon), research has shown that it is not known to produce hepatotoxic effects, and liver problems are extremely unlikely with this compound.
Proviron’s side effects do indeed include negative impacts on the cardiovascular system, however. Studies have shown that 100mg of Proviron daily for 6 months has shown very significant negative effects on cholesterol values, both increasing the bad (LDL) cholesterol and decreasing the good (HDL) cholesterol by 65% and 35% respectively.
It is also likely that Proviron may have a suppressive effect on endogenous natural Testosterone production (though this is considered to be very weak). Nevertheless, studies have demonstrated that 150mg or less per day of Proviron that no significant suppression of Testosterone results. In those same studies, higher dosages (300mg or higher per day) resulted in significant suppression of Testosterone levels.