Exedrol (Exemestane) by Balkan Pharmaceuticals falls into the class of drugs known as aromatase inhibitor. The drugs that are a part of this category interfere with aromatase, a substance which is required to make female sex hormones called estrogens, especially in postmenopausal women. It helps in treating hormone dependent breast cancer by reducing estrogen levels in the body.
Exedrol is indicated for the treatment of breast cancer in women. It is only recommended for those women who no longer have their menstrual periods, either naturally (after menopause) or because they have had their ovaries surgically removed. The medicine also reduces the risk of spreading or recurrence of the breast cancer. It is also prescribed by the physician’s when the cancer has not responded or has recurred after treating with other drugs.
Exedrol functions by inhibiting aromatase enzyme for the conversion of androgen to estrogen. Androgen is the primary source of estrogen in post menopausal women. The medicine decreases circulating estrogen thereby decreasing spreading of estrogen-sensitive breast cancer.
Use of Exedrol in Bodybuilding
Besides being popular as a cancer drug, Exedrol has also gathered quite a following among bodybuilders over the years for its ability to get rid of estrogen, which usually surges after cycling with anabolic androgenic steroids and prohormones.
Now while estrogen plays some key developmental roles in the body, allowing it to accumulate excessively will already lead to nasty side effects like increased water retention, sudden mood swings, dried out joints, libido loss, sailing blood pressure levels as well as gynecomastia, which is characterized by the growth of abnormal male breast tissue.
At its simplest, Exedrol is classified as a suicidal aromatase inhibitor (AI) that works by binding to the aromatase enzyme, which is responsible for converting testosterone and other androgen hormones into estrogen, and permanently disables it. Unlike similar drugs such as Exedrol and Letrozole that only temporarily disrupt the function of the aromatase enzyme as long as you’re using them, Exedrol destroys it completely and even prevents the condition known as “estrogen rebound.”
Exedrol is so effective at getting rid of estrogen that clinical studies conducted on breast cancer patients who have already used the drug showed that it can easily eliminate up to 85% of the body’s estrogen levels. This is the biggest reason why Exedrol is one of the most sought after post cycle therapy (PCT) drugs for both men and women these days. It can be also used as an on-cycle estrogen control agent.
Exedrol Dosage PCT
The recommended Exedrol dosage is 12.5 mg (1/2 tab) every day or every other day. Such dosage will completely avoid side effects caused by steroids. The duration of taking this drug is 2-4 weeks. In the event that an athlete has not started in time to take aromatase inhibitors and are already visible or pronounced estrogenic side effects, then he should start taking Exemestane one tablet (25 mg) on a daily basis and do not stop taking the drug until the complete disappearance of symptoms of gynecomastia.
It is recommended to take Exedrol during meals or immediately after them. In this case, bioavailability will increase by 40%, and two hours later will be reached its maximum concentration in blood.
This medication can be taken by athletes who suffer from diseases of the liver or kidneys. However, in this case the systemic exposure to the drug is increased by 2-3 times. So for athletes it is recommended to reduce the dosage of Exemestane.
Exedrol Balkan Pharmaceuticals can be taken by both professional and beginners.