Clomixyl (Clomiphene Citrate) by Kalpa Pharmaceuticals is a synthetic non-steroidal drug that is very similar in structure to estrogen. It is widely used as an ovulatory stimulant. Because of its similarity to estrogen, it can bind to the estrogen receptors in the hypothalamus. This blocks the hypothalamus from sensing “real” estrogen and the hypothalamus in turn acts by stimulating the pituitary to release more Gonadotropins like FSH and LH. The FSH and LH stimulate the ovaries/testes to produce more estrogen/testosterone.
This property of Clomixyl has been widely used to treat women with ovarian failure and induce ovulation. However, long term use of this drug may not be safe because of the increase risk of ovarian cancer.
Clomixyl is recommended for the treatment of women who have ovulatory dysfunction. Many women who fail to get pregnant have been found to have dysfunction in the ovulation cycle. Women with ovulation problems include those with polycystic ovarian syndrome and some with unknown causes of amenorrhea. Clomixyl is only prescribed after a thorough evaluation of the menstrual cycle is done to determine where the problem occurs. To achieve ovulation with Clomixyl, timing is of great importance. The woman’s body temperature is monitored and blood work is done to determine if ovulation has occurred.
Once ovulation is established, Clomixyl is started. In general Clomixyl is started on or about the 5th day of the cycle. Clomixyl is generally administered for 3-6 cycles. Long term therapy is not recommended.
Clomixyl for Men Bodybuilding
In men, Clomixyl also acts as a partial anti-estrogen, and may be used to counter some of the side effects of aromatizable steroid use including gynecomastia and increased water retention. As an anti-estrogenic drug, clomiphene citrate may also produce an elevation of follicle stimulating hormone, and luteinizing hormone levels, which can elevate testosterone production. This effect is especially beneficial at the conclusion of a steroid cycle, when endogenous testosterone levels are depressed.
Here, Clomixyl is most often applied in combination with hCG and tamoxifen, in an effort to restore endogenous testosterone production more quickly. If testosterone levels are not brought back to normal in a short period of time, a significant loss in size and strength may occur. This is due to the fact that without testosterone (or other anabolic/androgenic steroids) to impart an ongoing anabolic message, the catabolic hormone cortisol becomes the dominant force affecting muscle protein synthesis. Often referred to as the post-steroid crash, when not corrected this state of imbalance in the endocrine system can quickly reduce muscle mass levels, diminishing the long-term return on anabolic/androgenic steroid therapy.
Note that the triphenylethylene compounds (toremifene citrate, tamoxifen citrate, clomiphene citrate) tend to be somewhat intrinsically estrogenic in the liver. This means that while they can block estrogenic activity in some areas of the body, they can actually act as estrogens in this other key area. Estrogenic action in the liver is important in the regulation of serum cholesterol (it tends to support HDL synthesis and LDL reductions). Since steroid-using bodybuilders are already dealing with the negative cardiovascular effects of these drugs, compounding the issue with aromatase inhibitors (which will lower total serum estrogen levels) may not always be the best option. Using a drug that blocks gynecomastia, for example, while at the same time supporting improved cholesterol values, might be much more ideal.
Dosage of Clomixyl (Clomiphene Citrate)
Clomixyl should be taken strictly as indicated by the doctor. If you need to be explained or learn more detailed directions, do not hesitate to ask your doctor. Taking Clomixyl, you are strictly recommended to follow your doctor`s directions, because an exact dosage depends on individual health state of every woman.
However, the standard dosage of the drug is Clomixyl 50mg, taken for five days running of your menstrual cycle. Start from the first day of your menstrual bleeding, not first spots. It is a standard protocol of drug administration. Your doctor may indicate a different protocol other than you expected, for example, Clomixyl 50mg on the third day of menstrual cycle, in this case, buy cipro no prescription follow all his prescriptions, ovulation and pregnancy rates are believed to be similar under different administration ways. When you buy Clomixyl, store it at room temperature, away from heat, sun light, and moisture.